When Is IUI Recommended?
Typically, an IUI is performed if testing reveals a problem with natural sperm exposure at the time of ovulation, caused by such factors as:
- Abnormal mucus/sperm interactions
- Poor sperm motility
- Low sperm count
All patients undergoing ovulation induction are offered IUI to maximize success. Couples who have cryopreserved the intended father’s sperm can also benefit from IUI with frozen/thawed sperm, particularly if he has a busy travel schedule or is outside of the U.S. at the time of ovulation.
The IUI Process
IUI is a fertility treatment in which sperm is placed directly into the uterus to increase the chances of fertilization. The procedure begins with sperm collection, which is then processed in a lab to concentrate and prepare the healthiest sperm. A thin catheter is used to insert the prepared sperm into the uterus, bypassing the cervix to bring the sperm closer to the egg. Factors influencing the chances of a patient conceiving via IUI include:
- Woman’s age and egg quality
- Quantity and quality of the man’s sperm
- State of the fallopian tubes
Inseminations can be done during a patient’s natural menstrual cycle, during which the timing of insemination is determined by using an ovulation predictor kit (a urine test). The IUIs can also be enhanced by increasing the number of “targets” for the sperm by giving the woman medications that allow her to produce more than one egg. These more aggressive treatments include the use of injectable hormones and often increase the chances of having twins or triplets (called multiple gestation).
IUI with Donor Sperm
For those couples or single women in need of a sperm donor, we offer frozen/thawed donor sperm insemination 7 days a week and with the utmost discretion. For patients’ convenience, we accept shipments from the sperm bank of their choice and will hold the frozen sperm for up to three months at no additional charge. Our long-standing working relationship with California Cryobank (since 1991) has helped hundreds of patients see their family dreams come true.
What are the success rates of IUI?
At IVFMD, we understand that one of the first questions many patients ask about IUI is: Will it work for me? The answer depends on several personal factors, including age, diagnosis, sperm quality, and whether fertility medications are used.
On average, IUI has a per-cycle success rate of about 10-20% for individuals under 35. Success rates gradually decline with age, typically falling to 10-15% for patients between 35 and 40, and around 5-10% for those over 40. While these numbers may seem modest, they’re similar to the monthly chances of natural conception in couples without fertility issues.
Our team uses your unique medical history and fertility goals to guide your care. IUI can be a helpful first step for many individuals and couples, and we’ll always be honest about whether it offers a meaningful chance of success in your situation. Every treatment plan is thoughtfully tailored to give you the best possible outcome.